Topics: adverse drug reactions, pharmacovigilance

Topics: Pharmacogenomics, Pharmacoepidemiology, DRUG SPECIFICITY, receptor classification, drug concentration, drug effect, spare receptors, COMPETITIVE ANTAGONISM, Irreversible Competitive Antagonism, Partial Agonists, Constitutive Receptor Activation, Inverse Agonists, two-state receptor model, Biased Agonism, Allosteric Modulation, Chemical Antagonism, Pharmacokinetic Antagonism, Receptor–Response Linkage, Physiological Antagonism, Desensitisation, Tolerance, Altered Drug Metabolism, Binding Reaction, Drug–Receptor Interactions, Receptor mechanisms, Ion Channels, Enzymes, Receptor Proteins, Receptor Heterogeneity, Ligand-Gated Ion Channels, Gating Mechanism, G Protein–Coupled Receptors, Proteinase-Activated Receptors, G proteins, phospholipase C, inositol phosphate system, Inositol phosphates, intracellular calcium, Diacylglycerol, protein kinase, MAP kinase system, GPCR desensitisation, Biopharmaceuticals, Chemical Mediators, Presynaptic Modulation, Postsynaptic Modulation, Cholinergic transmission, Nicotinic Receptors, Acetylcholine, Muscarinic Agonists, Muscarinic Antagonists, Ganglion Stimulants, Ganglion-Blocking Drugs, Neuromuscular-Blocking Drugs, Non-Depolarising Blocking Agents, Depolarising Blocking Agents, Cholinesterase Reactivation, Noradrenergic transmission, Adrenoceptor Agonists, α-Adrenoceptor antagonists, 5-Hydroxytryptamine, migraine, Adenosine, purine, Histamine, local hormone, Eicosanoids, Prostanoids, Leukotrienes, Platelet-Activating Factor, Bradykinin, peptide, Neuropeptides, Cytokine, Interferon, Cannabinoids, Endocannabinoids, Nitric oxide, Ischaemic Heart Disease, Antidysrhythmic Drugs, Myocardial Contraction, Anti-Anginal Drugs, Organic Nitrates, Calcium Antagonists, Endothelin, Vasoactive Drugs, Vasodilator Drugs, heart failure, Atherosclerosis, lipoprotein metabolism, Lipoprotein Transport, Lipid-Lowering Drugs, Fibrates, Haemostasis and thrombosis, Blood Coagulation, Warfarin, Platelet Adhesion, Platelet Activation, Antiplatelet Drugs, Adenosine Receptor Antagonists, Fibrinolysis, Thrombolysis, Fibrinolytic Drugs

Topics: drug disposition, TDM service protocols, Drug assay techniques, Gas-liquid chromatography, High-performance liquid chromatography, Radioimmunoassay, Cardioactive drugs, Bronchodilators

Topics: Pharmacotherapeutics, Pharmacokinetics, Pharmacogenomics, Pharmacological effect, Therapeutic index, Therapeutic Range, Steady state, pharmacokinetic studies, Therapeutic drug monitoring testing, Minimum Effective Concentration, Maximum Therapeutic Concentration, Minimum Toxic Concentration, Half Life of a drug, First order kinetics, Zero order kinetics, Michaelis-Menten kinetics, Kinetic homogeneity, Antiepileptics, Antimanics, Antineoplastics, Bronchodilators, Chromatographic techniques, Thin layer chromatography, High performance liquid chromatography, Gas chromatography–mass spectroscopy, Therapeutic Range, Antiarrythmics, Antibiotics, Immunosuppressives

Topics: drug action, Altered GIT absorption, Chelation, drug-induce mucosal damage, Passive tubular reabsorption, PHARMACODYNAMIC INTERACTION

Topics: Sedative-Hypnotic Drugs, benzodiazepines, gamma-aminobutyric acid, Benzodiazepine Binding Site Ligands, Antiseizure Drugs, Phenytoin, Carbamazepine, Seizure Disorders, Status epilepticus

Topics: Psychopharmacology, Drugs, brain, behavior, Nervous System, chemical signaling, Catecholamines, Neurotransmitter Synthesis, Neurotransmitter Receptors, Synaptic Plasticity, Catecholamine Synthesis, Dopaminergic System, Noradrenergic System, Serotonin, Serotonin Synthesis, Serotonergic System, Acetylcholine, Cholinergic System, Glutamate, drug abuse, drug addiction, alcohol, Alcohol Use Disorder, Opioids, Narcotic Analgesics, Opioid Receptors, Endogenous Neuropeptides, Psychomotor Stimulants, Cocaine, Amphetamine, Nicotine, Caffeine, cigarette smoking, vaping, Marijuana, Cannabinoids, Hallucinogens, Ketamine, Mescaline, Psilocybin, Inhalants, Anabolic–Androgenic Steroids, Anxiety Disorder, Affective Disorders, Antidepressants, Mood Stabilizers, Schizophrenia, Antipsychotic Drugs, Neurodegenerative Diseases, Parkinson’s Disease, Alzheimer’s Disease, Huntington’s Disease, Amyotrophic Lateral Sclerosis, Multiple Sclerosis

Topics: Exogenous antigens, Injurious immune reactions, IMMEDIATE Hypersensitivity, TYPE 1 HYPERSENSITIVITY, Systemic anaphylaxis, Local immediate hypersensitivity, ANTIBODY-MEDIATED hypersentivity, TYPE 2 HYPERSENTIVITY, Opsonization, Membrane Attack Complex, Fc Receptor-Mediated Inflammation, Antibody-Mediated Cellular Dysfunction, IMMUNE COMPLEX-MEDIATED Hypersensitivity, TYPE 3 HYPERSENSITIVITY, Exogenous antigen, Endogenous antigen, SYSTEMIC IMMUNE COMPLEX DISEASE, Acute Serum Sickness, Acute Inflammatory Reaction, Fibrinoid Necrosis, LOCAL IMMUNE COMPLEX DISEASE, ARTHUS REACTION, Cell-mediated hypersensitivity, DELAYED TYPE HYPERSENTIVITY, GRANULOMATOUS inflammation, GRANULOMA, TYPE 4 HYPERSENSITIVITY

Topics: antimicrobial resistance, antiparasitic resistance, penicillins, tetracycline, cephalosporin, amphotericin B, Aminoglycosides, antifungal drugs, azole compounds, allyamines, Antimalarial resistance, Chloroquine resistance, Antifolate resistance, Artemisinin resistance, ANTIPARASITIC DRUG RESISTANCE, Trichomoniasis, Trichomonas resistance, Leishmaniasis, African trypanosomiasis, Trypanosomiasis drug resistance

Topics: vaccine opposition, vaccine Hesitancy, precision medicine, clinical care, disease prevention, Diagnosis, Palliative care, End-of-life care, pain, chest discomfort, abdominal pain, headache, back pain, neck pain, Fever, Rash, Nervous System Dysfunction, syncope, dizziness, vertigo, fatigue, numbness, tingling, sensory loss, Gait disorders, confusion, Dementia, Aphasia, memory loss, sleep disorders, eye disorder, smell disorder, hearing disorder, dyspnea, cough, hemoptysis, hypoxia, cyanosis, Edema, Palpitations, Dysphagia, Nausea, vomiting, indigestion, Diarrhea, constipation, unintentional weight loss, gastrointestinal bleeding, Jaundice, abdominal swelling, interstitial cystitis, bladder pain syndrome, Azotemia, urinary abnormalities, fluid disturbances, electrolyte disturbances, hypercalcemia, hypocalcemia, acidosis, alkalosis, Eczema, Psoriasis, cutaneous infections, acne, skin disorders, Immunologically Mediated Skin Diseases, Cutaneous Drug Reactions, Photosensitivity, interpreting Peripheral Blood Smears, anemia, Polycythemia, bleeding, thrombosis, pharmacology, Pharmacogenomics, oncology, hematology, neoplastic disorders, cancer genetics, cancer cell biology, cancer treatment, skin cancer, head cancer, neck cancer, breast cancer, upper gastrointestinal tract cancer, lower gastrointestinal cancer, pancreatic cancer, Gastrointestinal Neuroendocrine Tumors, Renal Cell Carcinoma, testicular cancer, Gynecologic Malignancies, Paraneoplastic Syndromes, Paraneoplastic Neurologic Syndromes, Autoimmune Encephalitis, Hematopoietic Disorders, Hematopoietic Stem Cells, Iron deficiency, hemoglobin disorders, Megaloblastic Anemias, Hemolytic Anemias, bone marrow failure syndrome, Polycythemia Vera, Myeloproliferative Neoplasms, Myeloid Leukemia, Acute Lymphoid Leukemia, Chronic Lymphocytic Leukemia, plasma cell disorders, Amyloidosis, transfusion therapy, Hematopoietic Cell Transplantation, Coagulation Disorders, hemostasis disorders, Antiplatelet Drugs, Anticoagulant Drugs, Fibrinolytic Drugs, infectious disease, microbial genomics, Pneumonia, clinical syndromes, community-acquired infections, lung abscess, infective endocarditis, Infectious Arthritis, Osteomyelitis, Intraabdominal Infections, Intraabdominal Abscesses, Acute Infectious Diarrheal Diseases, Bacterial Food Poisoning, Clostridioides difficile Infection, Pseudomembranous Colitis, Urinary Tract Infections, Pyelonephritis, Prostatitis, Sexually Transmitted Infections, Encephalitis, Acute Meningitis, Brain Abscess, Pneumococcal Infections, Staphylococcal Infections, Streptococcal Infections, Enterococcal Infections, Listeria monocytogenes Infections, Tetanus